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Old Thu, Feb-18-10, 13:47
Nancy LC's Avatar
Nancy LC Nancy LC is offline
Posts: 25,429
Plan: Paleo 99.5%
Stats: 210/170/160 Female 67.5"
Progress: 80%
Location: San Diego, CA
Default A statin trial with a placebo group

This is hilarious!


What did they do? Well it was more of the usual stuff but, back in the early years of this century, it was still considered ethical to include a placebo group in a statin trial! Gasp, horror, call the ethics committee.

Anyway, 54 people, all with known heart disesae, were allowed to go for 24 months without the benefit of atrovastatin. You wouldn't do this in the states! But here in Scotland, well, a few more heart attacks and no one will notice.

So what does a greater than 50% reduction of LDL-C and a near 50% reduction in C reactive protein do for CAC score progression?

Diddley squat, as you would expect. It's all the usual quotes:

"statin treatment does not have a major effect on the rate of progression of coronary artery calcification"
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