Wed, Sep-12-18, 05:36
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Plan: P:E/DDF
Stats: 225/150/169
BF:45%/28%/25%
Progress: 134%
Location: NC
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LDL-C Does Not Cause Cardiovascular Disease
LDL-C Does Not Cause Cardiovascular Disease: a comprehensive review of current literature
Drs. David Diamond and Malcom Kendrick are amongst the authors.
https://www.tandfonline.com/doi/abs...33.2018.1519391
Quote:
ABSTRACT
Introduction
For half a century, a high level of total cholesterol (TC) or low-density-lipoprotein cholesterol (LDL-C) has been considered to be the major cause of atherosclerosis and cardiovascular disease (CVD), and statin treatment has been widely promoted for cardiovascular prevention. However, there is an increasing understanding that the mechanisms are more complicated, and that statin treatment, in particular when used as primary prevention, is of doubtful benefit.
Areas covered
The authors of three large reviews recently published by statin advocates have attempted to validate the current dogma. This paper delineates the serious errors in these three reviews as well as other obvious falsifications of the cholesterol hypothesis.
Expert commentary
Our search for falsifications of the cholesterol hypothesis confirms that it is unable to satisfy any of the Bradford Hill criteria for causality, and that the conclusions of the authors of the three reviews are based on misleading statistics, exclusion of unsuccessful trials and by ignoring numerous contradictory observations.
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Sadly, Full article behind a paywall.
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