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Old Thu, Jan-24-02, 13:32
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Oldsalty Oldsalty is offline
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Post Inflamation as a cause of heart disease

Here is a quote from a recent article in the New York Times, the full article is at.
http://www.nytimes.com/2002/01/22/h...omy/22INFL.html


Scientist are coming to realize that inflammation may underlie many other common chronic diseases that come with aging, including atherosclerosis, diabetes, Alzheimer's disease and osteoporosis. Inflammation is also implicated in asthma, cirrhosis of the liver, some bowel disorders, psoriasis, meningitis, cystic fibrosis and even cancer.

Gradually, researchers put together a new narrative for heart attacks and strokes: immune-system cells that cause inflammation burrow into the artery wall and begin gobbling up droplets of fat. These fat- filled cells form a plaque and inflammation thins its fibrous cap. Eventually, the cap ruptures, and the plaque's contents spill into the bloodstream — along with pro-inflammatory cytokines, which encourage clotting. Suddenly, the artery fills with a cloud of rapidly coagulating blood cells. If the cloud is large enough, it forms a clot that blocks the artery and causes a heart attack or stroke.

A primary goal for heart attack prevention, Dr. Libby and others say, should be to keep inflammation to a minimum
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