Quote:
"The average minimum amount of carbohydrates needed to fuel the brain is 130g/day. .................the acceptable macronutrient distribution range for carbohydrates is 45 to 65% of calories."
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The wording makes it sound like the brain requires that much glucose
from our diet. It does not. The liver can produce all the glucose the brain requires out of the substrates like glycerol and some amino acids, all of which can come from the diet or the body's own fat and protein reserves. The liver also recycles certain substrate and converts them back into glucose. But, if we eat at least 130g of glucose per day, then the brain will use that much but not much more.
But why does the brain use that much when we eat glucose? Well, we could speculate that glucose is toxic above normal, and since the brain is the organ that consumes the most amount of fuel per weight, then it follows that the brain is the best organ for the job of disposing glucose as quickly as possible. I mean, why would it prefer glucose if when it runs on ketones, it does so 30% more efficiently? Or rather, when it runs on glucose, it burns 30% more fuel.
If we eat more than 130g of glucose per day, what happens with the surplus that the brain does not use? Well, it is used to replenish glycogen stores, to fuel other anaerobic activity, and to make us fat. Considering that glycogen stores are very small and quickly replenished, and that we do very little anaerobic activity, then it's logical to conclude that most of the surplus glucose we eat serves to make us fat. However, I learned that glucose is not converted to fat very well, probably only 20% of it. However more, glucose is converted to glycerol which is then used to bind fatty acids inside fat cells thereby allowing fat to accumulate above normal needs.
Also, glucose fed to worms shortens their life. So, when we eat glucose, and when our blood glucose rises above normal because of that, then perhaps it shortens our lives as well. I'm only guessing here but I'm pretty sure on this one.
Finally, regardless of how much glucose the brain uses, if we eat mostly refined and easily digestible carbs (which convert in glucose and other simple sugars), and if we eat at least 86g per day for twenty years, then we will suffer at least one disease of civilization if not more. Do I really care how much glucose my brain uses at this point?