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  #91   ^
Old Thu, Apr-11-19, 09:12
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 19,215
 
Plan: atkins, carnivore 2023
Stats: 200/211/163 Female 5'8"
BF:
Progress: -30%
Location: Massachusetts
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One thing led to another....

https://feinmantheother.com/2016/10...dies-will-help/


Quote:
Drugs employed as diabetes therapy, particularly metformin, have been found to have beneficial effects in cancer as well. Metformin reduces the risk of developing cancer although the effects on mortality are not clear cut.




Quote:
We cited an important study by Tannenbaum. He found, in 1945 (!) that a carcinogen-induced sarcoma in mice was repressed by reduction in total calories but if reduced by specifically lowering the carbohydrate intake, there was an enhanced response.


Quote:
It is now appreciated that the Warburg effect, the apparent reliance of tumors on glucose for fuel, is a key observation that has been insufficiently explored. The effect provides motivation and clues for exploring the metabolic approach to cancer. Warburg thought that all cancers showed this phenotype which is not true but a large number do; of significance is that one that does not, prostate cancer, is the outlier in the figure above on relation to diabetes.
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  #92   ^
Old Thu, Apr-11-19, 09:21
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 19,215
 
Plan: atkins, carnivore 2023
Stats: 200/211/163 Female 5'8"
BF:
Progress: -30%
Location: Massachusetts
Default

Biochemistry of energy use in layman's terms.

https://feinmantheother.com/2016/11...ies-might-help/


Quote:
We found that if you grow cancer cells in culture, ketone bodies will inhibit their growth and the amount of ATP that they can generate.




More explanation of energy use by cells--

https://feinmantheother.com/2016/12...warburg-effect/

Quote:
if we grow cancer cells in culture, acetoacetate (one of the ketone bodies) will inhibit their growth and will reduce the amount of ATP that they can generate. Normal cells, however, are not inhibited by ketone bodies and the cells may even be using them. Our working explanation is that the ketone bodies are inhibiting the cancer cell through the Randle cycle. Now, normal cells can maintain energy, that is compensate for the Randle cycle, by running the TCA cycle (in fact, that is the purpose of the Randle cycle: to switch fuel sources). The cancer cells, however, have some kind of defect in aerobic metabolism and can’t compensate. How does this happen? That’s what we’re trying to find out but we have a good guess.


THses three blogs were posted in 2016.
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  #93   ^
Old Tue, Jun-04-19, 08:38
TammyD's Avatar
TammyD TammyD is offline
Senior Member
Posts: 505
 
Plan: Gluten-free/Low Carb/IF
Stats: 250/220/175 Female 5'8"
BF:?
Progress: 40%
Location: Dartmouth Nova Scotia
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Thank-you Ms A., There is a lot to think about in this thread.
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  #94   ^
Old Wed, Jun-12-19, 08:13
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 19,215
 
Plan: atkins, carnivore 2023
Stats: 200/211/163 Female 5'8"
BF:
Progress: -30%
Location: Massachusetts
Default

You're welcome.

This is a journey..... solid information is slow to come by.

Talked to my mother the other day-- she is still solidly on board with chemo and radiation..... I dont think she can see how much her quick mind has slowed; it was obvious after the cancer treatment.

Praying methodology of treatments will improve as fast as possible.
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  #95   ^
Old Wed, Jun-12-19, 08:24
JEY100's Avatar
JEY100 JEY100 is offline
Posts: 13,430
 
Plan: P:E/DDF
Stats: 225/150/169 Female 5' 9"
BF:45%/28%/25%
Progress: 134%
Location: NC
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Quote:
Originally Posted by Ms Arielle
You're welcome.

This is a journey..... solid information is slow to come by.

Talked to my mother the other day-- she is still solidly on board with chemo and radiation..... I dont think she can see how much her quick mind has slowed; it was obvious after the cancer treatment.


Chemo Brain to us lay folk, the Doctors call it Cognitive Dysfunction
https://www.cancer.net/coping-with-...memory-problems Their strategies for coping with it limited, but maybe some of these will help.


Dr. Cantley's talk was yesterday, but as usual with these on-line summits, there should be a bonus day after Friday. He has some brand new studies on sugar and cancer. https://forum.lowcarber.org/showthread.php?t=482615
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  #96   ^
Old Wed, Jun-12-19, 09:34
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 19,215
 
Plan: atkins, carnivore 2023
Stats: 200/211/163 Female 5'8"
BF:
Progress: -30%
Location: Massachusetts
Default

Thanks Janet-- watching NOW. Missed the first couple days, dang, but Dr Noakes gave a very good synopsis of his adventures into low carbing.

Thank goodness for those that have the courage and will to stand up to the nay-sayers of low carb diets.
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  #97   ^
Old Sun, Sep-22-19, 12:20
JEY100's Avatar
JEY100 JEY100 is offline
Posts: 13,430
 
Plan: P:E/DDF
Stats: 225/150/169 Female 5' 9"
BF:45%/28%/25%
Progress: 134%
Location: NC
Default

A jam-packed newsletter from Dr Colin Champ, suggest anyone interested in cancer and healthy eating sign up for it. https://colinchamp.com/september-ne...aking-it-local/

He is now at Duke Cancer and I met with him for a second opinion on a lingering radiation side effect. That was about half the appointment, the other half we talked about Keto, his plans for a study with Dr Will Yancy and Eric Westman, and other area medical doctors and nutrition interests. Looking forward to his studies with Duke in the future.
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  #98   ^
Old Sun, Sep-22-19, 14:18
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 19,215
 
Plan: atkins, carnivore 2023
Stats: 200/211/163 Female 5'8"
BF:
Progress: -30%
Location: Massachusetts
Default

Wow, glad to see more on diet and prevention....
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  #99   ^
Old Sun, Sep-22-19, 18:47
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 19,215
 
Plan: atkins, carnivore 2023
Stats: 200/211/163 Female 5'8"
BF:
Progress: -30%
Location: Massachusetts
Default

Been runni g thru his material.

Uplifting to get support from an M D to continue focusing on diet like keto, and other tidbits like cole crops and spices etc and why HIIT works to fight cancer. And why high bmi is a risk : high estrogen output.

I knew the latter but for me personally my high body fat % seems to be at odds with a very low estrogen ( per blood test).

Janet, totally envy you have access to the best cancer doctors.
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  #100   ^
Old Sun, Sep-22-19, 21:07
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 19,215
 
Plan: atkins, carnivore 2023
Stats: 200/211/163 Female 5'8"
BF:
Progress: -30%
Location: Massachusetts
Default

Best info so far. I feel totallly vi dicated as with a couple years sluthing came to these same conclusions. Not that anyone bekeives me, but here is an MD whose study is just this.

https://youtu.be/iO7Y6rE3UBw

Dr collin champ md

https://m.youtube.com › watch
Colin Champ, M.D.: Cancer Prevention through Dietary Manipulation - Tangible Takeaways - YouTube

Hope the links work...
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  #101   ^
Old Sun, Sep-22-19, 22:35
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 19,215
 
Plan: atkins, carnivore 2023
Stats: 200/211/163 Female 5'8"
BF:
Progress: -30%
Location: Massachusetts
Default

Semi related....when change feels too difficult..

https://youtu.be/L51h8BBu7b8
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  #102   ^
Old Mon, Sep-23-19, 01:05
Meme#1's Avatar
Meme#1 Meme#1 is offline
Senior Member
Posts: 12,456
 
Plan: Atkins DANDR
Stats: 210/194/160 Female 5'4"
BF:
Progress: 32%
Location: Texas
Default

Quote:
Originally Posted by Ms Arielle
Best info so far. I feel totallly vi dicated as with a couple years sluthing came to these same conclusions. Not that anyone bekeives me, but here is an MD whose study is just this.

https://youtu.be/iO7Y6rE3UBw

Dr collin champ md

https://m.youtube.com › watch
Colin Champ, M.D.: Cancer Prevention through Dietary Manipulation - Tangible Takeaways - YouTube

Hope the links work...



That was long but I watched the first one and it was excellent! I've pretty much been cooking all of my meats in bacon drippings (lard) as study showed excellent results for fat in that one study.
Just like the golden chicken fat, that's what's healthy not soy bean, corn oil, or the no name vegetable oil...

I'll watch the second one tomorrow when there's more time.
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  #103   ^
Old Mon, Sep-23-19, 03:29
JEY100's Avatar
JEY100 JEY100 is offline
Posts: 13,430
 
Plan: P:E/DDF
Stats: 225/150/169 Female 5' 9"
BF:45%/28%/25%
Progress: 134%
Location: NC
Default

Dr Champ has given three talks at TheIHMC, one StemTalk podcast with the IHMC hosts, and a talk at the Ohio State Keto forum that was less then 30 minutes.

The funniest coincidence after I made the appointment and pulled out my radiation history file, found that in 2012 I had faxed Dr. Champ's first big study to my radiation oncologist, who due to various practice mergers over the past 13 years, is now with Duke too.

This one: https://scholar.google.com/citation...AJ:YFjsv_pBGBYC
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  #104   ^
Old Mon, Sep-23-19, 08:39
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 19,215
 
Plan: atkins, carnivore 2023
Stats: 200/211/163 Female 5'8"
BF:
Progress: -30%
Location: Massachusetts
Default

This makes total sense.

A study in 2005-6 showed better treatment outcomes when fasting was included the days of treatment with chem or radiation , cant remember which now. That study was nearly 15 years ago. Research seems so slow.

I suspected long ago the Dana Farbers of the world are not interested in prevention. So as a resource have prooven completely useless.

Thrilled to know Dr Champ is looking toward prevention.
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  #105   ^
Old Mon, Sep-23-19, 09:02
LCer4Life's Avatar
LCer4Life LCer4Life is offline
Senior Member
Posts: 692
 
Plan: Atkins
Stats: 155/143/125 Female 63
BF:33.2/28.7%/24%
Progress: 40%
Default

Great info. Will be watching podcasts & videos by Dr. Champ. Thanks!
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