Melatonin - Good morning to an unexpected culprit in type 2 diabetes

If you enter MELATONIN in the searchbar at the above link you find a series of presentations on these topics.

Basic science of circadian rhythms, melatonin and melatonin receptors

Pancreatic Melatonin Receptors: From Fiction to Function

The genetics of the melatonin receptor 1B in type 2 diabetes

Melatonin Diabetes Google Scholar search of recent papers Just reading the titles gives an idea of where this research is leading.
Interesting to see that Seasonal Changes in Mood and Behavior Are Linked to Metabolic Syndrome

and

Less need for insulin, a surprising effect of phototherapy in insulin-dependent diabetes mellitus

If you listen to the 3 talks I linked to at the beginning of this post you'll understand why it is that light therapy in the morning switches off the melatonin production and as melatonin inhibits insulin secretion the pancreas is better able to produce it.

Shift work and type 2 diabetic patients' health.

Daily Melatonin Administration at Middle Age Suppresses Male Rat Visceral Fat, Plasma Leptin, and Plasma Insulin to Youthful Levels

But remember that rats have a different circadian rhythm than humans but we see here that is disrupted by constant light and it interesting to speculate if street lighting, use of nightlights in kids bedrooms, kids now not going to bed early evening and being expected to stay in bed till the morning but keeping the same hours as their parents often, digital displays on bedroom musis/pc/tv gadgets will all reduce the circadian rhythm and all this is exacerbated by folks of all ages not spending enough time outdoors in full daylight.

and there is probably also a seasonal component.

As pigs have both a circadian rhythm (similar to humans) and a gall bladder(showing they evolved to eat animal fat similar to humans) they would make much better experimental model for nutritional modelling than rats.

I wonder if any of you have noticed if your insulin requirement to a set meal changes depending on the time that meal is eaten?
ie Is the response to a midday meal (when melatonin levels are lowest) exactly the same as the response at 9pm to an identical meal (when meltonin levels should be rising)