Thu, May-04-23, 03:42
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Plan: P:E/DDF
Stats: 225/150/169
BF:45%/28%/25%
Progress: 134%
Location: NC
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Since I am now more focused on preserving and increasing lean muscle mass and bone density as I age, this new article on a longer term result of Ozempic caught my eye:
Ozempic Can Cause Major Loss of Muscle Mass and Reduce Bone Density
Quote:
-Rapid weight loss from taking GLP-1 medications like Ozempic and Wegovy can cause a decrease in muscle mass, lessen bone density, and lower your resting metabolic rate, leading to sarcopenia.
-Sarcopenia is the gradual loss of muscle mass, strength, and function and is typically associated with aging.
-Lifestyle changes such as increasing protein intake and incorporating strength and resistance training can help combat muscle and bone density loss while taking GLP-1 medications.
Many people taking glucagon-like peptide 1 (GLP-1) drugs like Ozempic or Wegovy (semaglutide) and Mounjaro (tirzepatide) experience rapid weight loss.
“According to a clinical trial of Ozempic, after 68 weeks on the medication, 86.4% of participants lost 5% or more of their body weight, and 69.1% lost 10% or more of their body weight.”
While weight loss can bring about health benefits, losing weight rapidly can also cause a decrease in muscle mass, lessen bone density, and lower your resting metabolic rate, leading to sarcopenia — the gradual loss of muscle mass, strength, and function.
“Sarcopenia affects the elderly population and typically is associated with aging. However, rapidly losing weight with GLP-1s like Ozempic or Wegovy without the proper diet and exercise can also cause sarcopenia (sometimes referred to as ‘skinny fat’) at any age, negatively affecting a person’s quality of life by reducing their stamina and ability to perform daily activities, such as easily walking up stairs,” Dr. Rekha Kumar, a practicing endocrinologist in NYC and Chief Medical Officer of Found, told Healthline.
Sarcopenic obesity mimics obesity, she added, and occurs when a person’s BMITrusted Source is in the normal or low range, but their levels of lean muscle are so low that fat and bones are the only metabolically active tissue.
“[It’s] important to note that a lower body weight does not always mean that a person is healthier. After some weight loss is achieved and a person reaches a plateau, it is important to assess body composition.”
Continues at:
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https://www.healthline.com/health-n...uscle-mass-loss |