Guaifenesin is blocked by most plant based supplements - spirulina, garlic oil etc. When I first started many years ago, I quit ALL medications & supplements & then tried to add them back in after I found out how guaifenesin worked. I found the guaifenesin helped more than other things I was using - like daily B12 injections, which had helped the most to that point. I got MUCH worse for a few days before I got better. It is NOT a cure but for me it does manage the pain. If I miss a day or take something that blocks it, I can tell.
Guaifenesin (Mucinex) is fairly inexpensive. I get mine from ebay. When the protocol first came out & it was a prescription drug, it was CHEAP. Mucinex stopped competition and prices doubled but it's still cheaper than anything else and I can't bear the pain and I hate the thought of anyone else suffering.