Sun, Apr-30-06, 20:27
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Plan: Paleoish/Keto
Stats: 225/167/175
BF:18%
Progress: 116%
Location: Longmont, Colorado
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Glucosamine has been mentioned as increasing insulin resistance. There is a clinical trial (not started yet) that will try to determine if there is any truth to this. An excerpt from the trial proposal is
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Glucosamine is a popular over-the-counter nutritional supplement that many people use for the treatment of osteoarthritis. Intravenous administration of glucosamine to animals or humans causes significant metabolic insulin resistance and vascular endothelial dysfunction. Moreover, experiments with various cell lines have implicated elevated glucosamine levels in the development of insulin resistance. However, there are no published studies examining the potential effects of oral glucosamine administration to modulate insulin sensitivity or capillary recruitment in humans.
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If you are insulin resistant, you may want to avoid glucosamine until more data is available. |