I'm 56 and heres my story. I started going thru it in my mid 40's. They were nice and let me stay on HRT until recently. Doc decided that I needed to be off. Well that hot flashes were coming fast and furious until I found a combination of supplements to help a little. They are at least bearable now and the good thing is nobody can tell me I have to quit taking it. For awhile i didn't think I was ever going to get them under control, so I desperately called the doctors office and said I needed the hormones back, but then the supplements kicked in so I cancelled my appointment. So that is my story, only I haven't figured out how to stop night sweats. Judy