Weight loss. It would be hard to track impact on hormones, and especially atutophagy, short term. Members are always asking how long to fast for autophagy benefits, will coffee stop autophagy, etc. etc. so the moderators now have a file and stock answer...no one knows! I went off the LC ranch this holiday season and 42 hour fasts are working well to shed the pounds...until it stops. But for now, I see a benefit to 42 hours for weight loss, and with four years of fasting experience and a clean VLC diet, I have zero hunger. Sort of amazing to compare how I felt in 2014 first starting IF.