Sat, May-07-22, 12:59
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Plan: Paleoish/Keto
Stats: 225/167/175
BF:18%
Progress: 116%
Location: Longmont, Colorado
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New obesity drug
https://www.nytimes.com/2022/04/28/...ide-wegovy.html
Excerpts from the article"
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An experimental drug (Tirzepatide) has enabled people with obesity or who are overweight to lose about 22.5 percent of their body weight, about 52 pounds on average, in a large trial, the drug’s maker announced on Thursday.
The company, Eli Lilly, has not yet submitted the data for publication in a peer-reviewed medical journal or presented them in a public setting. But the claims nonetheless amazed medical experts.
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The results do seem to be amazing.
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The Eli Lilly study lasted 72 weeks and involved 2,539 participants.
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Quite a long study.
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Patients injected themselves with the drug once a week.
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I am surprised that they got the subjects to inject themselves weekly for over a year. I have a needle-phobia and could not do that.
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But prices may be a barrier. Insurers often will not pay for weight loss drugs. The Novo Nordisk drug, whose brand name is Wegovy, has a list price of $1,349.02 per month.
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If the price is anywhere near that then most people needing it could not afford it; especially since it is every month for the rest of your life.
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All received diet counseling to reduce their calorie intake by about 500 a day.
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Reducing calories is not something that most people can do long-term, even with counseling. I wonder if the participants for the study were specially selected.
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The medications are among a new class of drugs called incretins, which are naturally occurring hormones that slow stomach emptying, regulate insulin and decrease appetite. The side effects include nausea, vomiting and diarrhea. But most patients tolerate or are not bothered by these effects.
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I would be very bothered by nausea, vomiting, or diarrhea. Those side effects would definitely cause me to lose weight though!
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Diet and exercise, combined with earlier obesity drugs, usually yield perhaps a 10 percent weight loss in patients. That is enough to improve health, but not nearly enough to make a big difference in the lives of peoples who are obese.
The only other treatment is bariatric surgery, which can result in substantial weight loss. But many people are ineligible or simply do not want the surgery.
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So, the only methods that they can come up with are the traditional diet (low-fat) and exercise. I have had great results with low-carb eating and have enjoyed the good results for 20 years with no drug cost.
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