This is a great thread. One of my main motivators for this WOE is brain health (and heart, liver, pancreas, kidneys, etc.); prevention of dementia and Alzheimer's disease. To me, weight loss is secondary and a bonus. I just started reading Amy Berger's The Alzheimer's Antidote (2017) and just put on hold Dale Bredesen's The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline (2017).