Ya, Fibro is really bad sometimes, and all you can do is try to cope.

When she feels up to it, looking into the various causes might lead her to a bit of help. Sometimes the cure is not pleasant either... one that that helped me was getting my root canaled teeth and the silver amalgams [mercury] filling teeth removed. Actually, I ended up getting all my teeth removed and I am in full dentures now - and glad I did it... no more dentists and no more pain,plus it really really helped the Fibro too.

I had trigeminal neuralgia, and when the teeth were removed, all that pain ended right away.

So did most of my migraines, and about 80% of my "fibro muscle pains".

No more calf cramps while standing in the grocery line, no more twitching calves in the mornings.

Those neck pains from turning my head suddenly, and then a terrible headache, went away. Neck pains and teeth are very much linked. Eye pains too.

Sorry, I ended up talking about myself, isn't that typical. Just trying to relate what helped me - I really hope your sis can find some answers.