I'm confused about the message of the article. My first impression is that they are trying to discuss the biological underpinnings of weight loss and gain. But the author ends the article with the same tired idea that somehow she should have been able to stop herself from gaining weight. What is the point? It seems like the idea of gluttony and sloth = fat is so difficult to kill. With all the emerging science, the underlying message still seems to be about willpower and virtue. I think the article has a lot to offer, but given the length of it, it could have covered a lot more ground.