On the subject of Splenda, on one hand you can't compare the covalent chlorine bond with ionically bound sodium chloride. A covalent chlorine-carbon bond is found in methylene chloride, and that is hardly a healthy substance.

On the other hand, Splenda does not appear to be especially toxic, and since you are consuming 1/200th of the amount as you would of sugar (due to the sweetness) you are not getting much of an exposure if you use the stuff in moderation. I have chosen to use it myself, to me it is the lesser of the two evils (sugar being the other alternative). I find I am slowly losing my sweet tooth, although I don't expect to ever get away from sweet things since I grew up on them and it is likely too firmly ingrained in my sense of pleasure/good taste.