Hi Lady,

I can somewhat relate to your issues.
First, let me tell you that synthroid is a T-4 hormone / cytomel is T-3.
Synthroid takes about 6 full weeks before you notice any changes in feeling, etc.
Cytomel takes effect immediately.
I tried the cytomel weight loss theory - it didn't work!
The synthroid/cytomel combo did make me feel better though - was less depressed, etc. but the weight loss didn't happen!
I wouldn't increase dosage though. That could be dangerous and if you read the web site (Cytomel) it says you shouldn't use cytomel for weight loss for more than two weeks!
Soooo, I'm sure there must be some ill effect to it.

Good luck and I hope you find what works for you!