Hi Debbie,
Thanks, yep -- god only knows, but it does seem like there is a whole lot of stuff going on that is still "black box."
They've discovered, for example, one or more genes that very clearly code for alcoholism in native americans. Two people can sit down and have a drink and one that barely drinks now and then can become horribly addicted, and another that drinks like a fish still might not be years later. So, would it seem appropriate to apply the same "Quit whining and just use willpower to get your shit together" approach with both people? We could, but it would be inequal, to say the least. Would that mean that it's impossible for the first person to "quit whining and get their shit together" and successfully reform and stay that way? Not at all. It just means that when there is gene expression supporting an addiction, the % of people with that addiction is likely to be huge, and the % of people who can successfully address is likely to be small, and how "hard or easy" it is for a person to deal with that brain-response is definitely going to depend on genetics in that case.
I'm not suggesting that neuro-addiction is the cause of severe obesity (that would be putting it back into the calories equation which I do not believe). I'm suggesting that gene expression is probably setting why anybody's body "allows" them to gain only 10 pounds and then they have cancer or diabetes, or allows them to gain 400 pounds and then mysteriously they still don't have either, although the fat cell quantity starts causing its own separate issues. I suspect some body "mapping" in DNA evaluates what it's going to allow to fit into the map so to speak. I expect within that larger body-map setting, then things like insulin etc. become the numbers in the formula. But clearly it can't just be insulin at work since as noted, plenty of people grow up eating about the same and even from the same family and yet are dramatically different at some point.
Both my sisters (different father) are short (one is 4'11). 1 was fat growing up, but has been thin since adulthood. 1 was lean growing up, but has been mostly heavy to fat since adulthood (excepting early marine corps days (!), and in fairness, how much extra weight can you carry without looking fat when you're only 4'11?!). The lean one has basically been living on under-calorie'd dry toast and skim milk with cereal and bran and stuff like that since she was a teen (not sure if this, or if simply growing out of so-called babyfat, is why the change for her), and exercising like a hamster (she was manager of a Holiday Spa for a long time, and the aerobics/spinning queen). She has other issues, they just aren't about fat.
Meanwhile, the only issues I have are ONLY related to my excess fat. When I get back down to 370 or so (which I consider inevitable, though I also think it eventually returning again -- in a cycle -- is also possibly inevitable) it'll be ok again; I am ridiculously healthy aside from the fat element. Almost never ill, very strong bones even as a kid, very athletic and coordinated even when I was young, and up to about age 29 and 300# (to the degree possible at that weight since I was very sedentary at work and worked way too much -- but I still played tennis, windsurfed, kayak'd, etc. until I got married and pregnant, and it was after that, which I know in retrospect corresponds to a sudden major 'reaction' to gluten and sudden effects (though it was likely gradual) of sleep apnea (Low Oxygen: the #1 cause of obesity in ME at least... in part because it drives insane carbs-for-energy intake) that I gained another couple hundred pounds).
It's a stats game, and I suspect that major obesity is incredibly like the alcoholism issue. It's quite clear that the human body has setpoints on degree of fat it will even allow a person to accumulate, just from observing 'the world'. My cousin grew up eating crap, still eats crap, still is so skinny that she's been hospitalized twice because her bodyfat is so low her body wants to eat her organs and no, she is not T1 diabetic (the obvious first place to look in that case) either. Another cousin is the same except not sick, still thin, and lives on beer and pizza and big quantities of it (a man). I grew up eating crap, 'mostly' eat well now though definitely not always, and had a high weight of over 500#. It's not merely a matter of food-based-insulin in my opinion because I don't think either of their bodies would LET them reach this weight. I don't know what it is about our bodies that makes them operate so differently, but I am tempted to think it is more than 'just' food in the equation.
As my post said too, I think you're right about the body possibly reacting to the speed of fat lost, although I suspect it may also be reacting to the state of nutrient depletion and caloric intake as well. Who knows for sure.
Re: TDC, I find that one of the main differences in how people approach lowcarb (or whatever they're doing) is often geared to how long they have been doing it and what their results have been. Everyone, no matter what weight, tends to overdo it to begin with. Depending on the person and how much weight we're talking about though, that often gets them down far enough to really pick up working out for example, and they may be able to maintain that point. People who have been working an eating plan(s) for years but have not reached a so called normal weight, or in many cases who lost a lot of weight, but then regained, but then lost, but then regained... it changes how people view it -- eventually. I think eventually people start realizing that what they were doing wasn't working for them in the long run, and that focusing on health as an overall issue is probably better for them than focusing on carbs/calories.
But when people begin, that latter focus is important and a big deal, and believing you CAN lose the weight is often motivational and even necessary. I was very skeptical about LC when I first encountered it, and it was a long time before I tried it. I had a whole family of women who'd dieted nearly every day of their life on every imaginable plan and after 20-40 years they were all still morbidly obese. That is why, after my initial month of lowcal dieting when I gained ~200# in my 20's, I never dieted after that. It was pretty clear that this was not productive, and merely led to decades of angst and misery and neurosis. Now, if I had known about low-carb and bodybuilding I think I could have dealt with that initial weight gain or at least part of it and been vastly better for it. Although I gained about 75 pounds over the next 12 years, this is with not dieting at all and often working every waking hour and not sleeping enough, and is not a lot of weight per year. I didn't add another ~200# until the whole gluten/apnea/sleep-deprivation/megastress element came back into my life (the latter two were involved in the first big gain cycle).
Anyway, I ask myself, when I had begun, if someone had told me, the most you're likely to lose will leave you at about 300# (which at the moment I'd be damn happy for mind you), would that have demoralized me? Discouraged me? I think so. Maybe it was necessary I had unrealistic expectations to begin, in order to get me to begin in the first place.
The body changes. Lose 150# and the body is not the same body you started with, plus it is in 'reaction' to what you just did. So part of this is not just about being super fat, but about the fact that possibly no eating plan is going to work 'the same' for someone when they begin as when they have lost a lot of weight -- it might just be that the more weight we're talking about, the more extreme that situation.
PJ
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