Quote:
Originally Posted by Dodger
In looking to see if I could quickly find the 30 carb number, I came upon this interesting tidbit about high blood-sugar levels and the brain. Too much glucose is not good for the brain.
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Not that high blood sugar is good, but the loss in intelligence is probably more a result of the energy-starvation from hypoinsulinemia in T1 diabetics (which has hyperglycemia as a symptom). That's why it's temporary when blood sugars rise briefly, but permanent once ketoacidosis onsets.
The temporary flux in blood sugar symbolizes a temporary energy deprived state, one that is not prolonged. As an approximation, it is probably parallel in severity to the energy-deprivation of more extreme hypoglycemia (although the mechanisms at work are very different).
As a hypoglycemic let me tell you that if you gave me any sort of test when I'm in a
severe hypo, I am likely to misspell all my words and barely make sense (zombie-like speech). It literally feels like slipping out of consciousness, I lose the ability to make sense of my environment, I lose contact with the emotional connotation of things... it's like a waking death (I have moments where I am aware of what's happening, but also can't control it and feel as if I'm "drifting").
Once a T1 progresses to ketoacidosis, energy starvation has become severe, life threateningly severe. Keep in mind when I speak of "energy starvation" I'm not talking about not eating - the body still fuels itself quite well on its tissues when not eating. I mean energy starvation in the most basic cellular sense - the body cannot fuel itself due to some sort of metabolic disease which prevents synthesis of energy to sustain life (whether or not you eat food is a non-factor). When a condition like that (T1 diabetes) progresses to a point, then irreversible damage happens to the body, part of it neurological.
It's like, if you fall into coma or have a stroke (oxygen, thus, energy deprivation), you are also very likely to suffer some degree of brain damage as well. It's not really the stroke or the coma that causes brain damage, but the oxygen (energy) deprivation that results. I imagine it's the same thing with hyperglycemia (particularly T1s after ketoacidosis episodes which is a SEVERE state of emergancy...)
It seems to correlate with hyperglycemia mainly because hyperglycemia is a marker for energy starvation & metabolic diseases.