Thu, Oct-07-04, 20:12
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Registered Member
Posts: 220
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Plan: n/a
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Quote:
Originally Posted by mle_ii
I'm curious as to why this is the case. Perhaps it makes sense for muscles, but why is it when the ankle inflames they recommend ice? What is the body doing when it induces inflamation? (I've got weak ankles so I sprain them quite a bit, though I haven't done it in some time now, knock on wood.)
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1. NSAIDs drastically reduce post-exercise protein synthesis.
2. They can do a number on your stomach in the long-term (and possibly the short-term).
3. Often, the NSAIDs are just providing symptomatic relief; in other words, are they just mask the pain instead of actually reducing the causative inflammation.
It has to do more with acute vs. chronic use. While it is beneficial to get past the inflammation stage ASAP with high-dose NSAIDs with acute injuries, they markedly blunt protein synthesis, which is a crucial factor in tissue regeneration, etc. The use of anti-inflammatories can also reduce prostaglandin synthesis, which is part of the pain signal, but also a part of the hypertrophy process as well, which can mean a lack of growth or a negative protein balance in a chronic setting.
NSAIDs certainly have a place in acute inflammation scenarios, as in the case of a traumatic injury or the initial onset of tendonitis. Decrease the inflammation with very high doses, and you can get into the initial stages of physical therapy much sooner
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