Active Low-Carber Forums
Atkins diet and low carb discussion provided free for information only, not as medical advice.
Home Plans Tips Recipes Tools Stories Studies Products
Active Low-Carber Forums
A sugar-free zone


Welcome to the Active Low-Carber Forums.
Support for Atkins diet, Protein Power, Neanderthin (Paleo Diet), CAD/CALP, Dr. Bernstein Diabetes Solution and any other healthy low-carb diet or plan, all are welcome in our lowcarb community. Forget starvation and fad diets -- join the healthy eating crowd! You may register by clicking here, it's free!

Go Back   Active Low-Carber Forums > Main Low-Carb Diets Forums & Support > Low Carb Health & Technical Forums > Dr.Bernstein & Diabetes
User Name
Password
FAQ Members Calendar Mark Forums Read Search Gallery My P.L.A.N. Survey


Reply
 
Thread Tools Display Modes
  #1   ^
Old Wed, Nov-22-00, 17:24
tamarian's Avatar
tamarian tamarian is offline
Forum Founder
Posts: 19,570
 
Plan: Atkins/PP/BFL
Stats: 400/223/200 Male 5 ft 11
BF:37%/17%/12%
Progress: 89%
Location: Ottawa, ON
Lightbulb

Wednesday November 22 2:05 PM ET
Gene Therapy Used to Cure Rodents with Diabetes

LONDON (Reuters) - Scientists said on Wednesday they have used a new type of gene therapy to cure diabetes in mice and rats which could pave the way for new treatments for millions of people with the disease.

Diabetes is a chronic disease that begins in childhood or early adulthood. Sufferers produce little or no insulin, a hormone that regulates blood sugar levels, and must rely on a strict diet or intravenous injection to control the disorder.

But researchers at Yonsei University in Korea and the University of Calgary in Canada have developed a technique to deliver an altered human insulin gene into mice and rats suffering from type one diabetes.

``This new gene therapy may have potential therapeutic value for the cure of autoimmune diabetes in humans,'' Ji-Won Yoon, of the University of Calgary, and his colleagues said in a report in the science journal Nature.

People with type one diabetes produce no insulin because their body destroys the insulin-secreting beta cells in the pancreas.

The scientists delivered the altered insulin gene into the diabetic rodents with a modified virus injected into the animals.

After the animals were treated, the altered gene kept the animals' blood sugar at normal levels during the eight-month study.

Although the results are encouraging, Jerrold Olefsky of the University of California in San Diego said it is still a huge leap from treating animals to humans.

``Rodents are quite different from humans with respect to maintaining glucose (sugar) levels, and extending these results to human physiology may prove a challenge,'' he said in a commentary in Nature.

One of the biggest challenges would be getting the insulin levels right because secretions of the hormone change with diet, age, weight and growth status.

``So a gene-therapy approach must be able to modulate insulin delivery in response to changing needs over time,'' he said.

``Despite these issues, the paper represents a good example of how basic research can be applied to problems of clinical significance,'' he added.


http://dailynews.yahoo.com/h/nm/200...genes_dc_1.html
Reply With Quote
Sponsored Links
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Similar Threads
Thread Thread Starter Forum Replies Last Post
Celebrity Chefs Across the Nation Crusade for Diabetes Awareness tamarian Dr.Bernstein & Diabetes 3 Tue, Dec-07-04 16:38
Insulin therapy unsuccessful in delaying or preventing onset of diabetes Voyajer Dr.Bernstein & Diabetes 0 Tue, Jul-30-02 13:41
Many Obese Youth Have Condition that Precedes Type 2 Diabetes IslandGirl LC Research/Media 0 Mon, Apr-15-02 16:53
Gene Therapy Used to Cure Rodents with Diabetes tamarian General Health 0 Wed, Nov-22-00 17:24
Celebrity Chefs Across the Nation Crusade for Diabetes Awareness tamarian General Health 0 Tue, Oct-31-00 18:32


All times are GMT -6. The time now is 22:52.


Copyright © 2000-2024 Active Low-Carber Forums @ forum.lowcarber.org
Powered by: vBulletin, Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.