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  #1   ^
Old Mon, Aug-11-03, 08:14
Mefisto Mefisto is offline
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Default High-Fat Meals: Acute Effects on the Heart

Another one which makes me a little nervouse

Acute Coronary Effects of a Fatty Meal
The long-term consequences of hyperlipidemia are well known, but can a single high-fat meal have acute coronary consequences in young, healthy men? Using transthoracic Doppler echocardiography, researchers studied coronary blood flow in the left anterior descending arteries of 15 men (mean age, 29) before, and 5 hours after, they consumed single high-fat meals (total fat, 100 g; saturated fat, 50 g; cholesterol, 300 mg). Within 1 week of consuming high-fat meals, 5 of the men underwent echocardiography before and after they ate single low-fat meals. Coronary flow reserve was calculated as the ratio of peak diastolic flow velocity (cm/second) after adenosine injection to flow velocity before injection.
Five hours after participants ate high-fat meals, mean coronary flow reserve had decreased from 4.02 to 3.30 (i.e., by 18%). For the 5 men who consumed both meals, mean coronary flow reserve decreased by 0.79 after the high-fat meal and increased by 0.07 after the low-fat meal.
Comment: A high-fat meal can impair coronary flow reserve, mainly by impairing peak coronary flow velocity. It is unknown whether such impairment can precipitate clinical events (e.g., myocardial infarction) in young, healthy people. However, if these findings apply to people with coronary artery disease, then high-fat meals could, at least theoretically, lead to cardiac ischemia in CAD patients.
— Richard Saitz MD, MPH
Published in Journal Watch April 9, 2002
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  #2   ^
Old Mon, Aug-11-03, 17:21
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mariejoe mariejoe is offline
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Wouldn't you have to eat, like almost 3 cheeseburger with bacon to consume THAT much fat?
I don't think any low carbers eat that much fat PER MEAL, maybe not even per day.
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  #3   ^
Old Tue, Aug-12-03, 01:51
Mefisto Mefisto is offline
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Yes I agree but I wonder how low you have to keep your fat intake per meal to avoid this effect.
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  #4   ^
Old Tue, Aug-12-03, 05:53
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mariejoe mariejoe is offline
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I think for a long-term L/C lifestyle, you should consume more of the healthy fats, like butter and olive oil, than other less healthy fats, like bacon.

My doctor recommended I back off from a lot of cheese, opting for lower-fat cottage cheese or regular plain yogurt. Also, cheese and bacon can have a lot of salt in it

Bottom line: quality fats instead of fat for fats sake.
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  #5   ^
Old Tue, Aug-12-03, 17:28
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Lisa N Lisa N is offline
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Quote:
Comment: A high-fat meal can impair coronary flow reserve, mainly by impairing peak coronary flow velocity. It is unknown whether such impairment can precipitate clinical events (e.g., myocardial infarction) in young, healthy people. However, if these findings apply to people with coronary artery disease, then high-fat meals could, at least theoretically, lead to cardiac ischemia in CAD patients.


This really isn't anything new. It's been known for quite some time that after a heavy meal, blood flow is redirected to the stomach for the time that it takes to digest the meal and since fat and protein take longer to digest than sugars and carbohydrates, I would have expected the result that they got.
However...100 grams of fat at one meal is a bit excessive by any standard. That's only a bit less than what I would get in an entire day, let alone in one meal. They also don't mention the other components of the participant's high fat meal (how much protein and carbohydrate they also consumed).
Some other questions that I would have is what about the other 10 men? There were a total of 15 participants in the study, yet they only give the test results for 5 of them. That smacks of only giving stats on the participants that showed the results that they were after. They also say that only theoretically could such a meal cause a problem even in those with existing ischemic heart disease (in other words, they did not actually observe this effect to occur and it's unknown whether it would or not) and that they basically have no idea of the effect that it would have on a person with a healthy heart.
So...what we have here is a study that shows that blood flow is redirected to the stomach after a heavy meal (something that medical science already knew) and is redirected less and for a shorter period of time after a light meal.
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