some more ammo:
http://www.nutritionandmetabolism.com/content/1/1/2
http://www.pubmedcentral.nih.gov/ar...ubmedid=7000826
http://jap.physiology.org/cgi/content/abstract/71/1/197
excerpts from the first article cited:
The energy expenditure data (expressed as oxygen consumption) and exercise times across this 8-week inpatient study are shown in Table 1. That these subjects'peak aerobic power did not decline despite 6 weeks of a carbohydrate-free, severely hypocaloric diet implies that the protein and mineral contents of the diet were adequate to preserve functional tissue. As can be noted, endurance time to exhaustion was reduced after one week of the ketogenic diet, but it was significantly increased over the baseline value by the 6-week time point. However the interpretation of this endurance test is confounded by the fact that the oxygen cost (ie, energy cost) of the treadmill exercise had significantly decreased following the weight loss, and this occurred despite the subjects being made to carry a backpack loaded to bring them back to their initial exercise test weight.
This question of improved efficiency notwithstanding, it is clear that our subjects experienced a delayed adaptation to the ketogenic diet, having reduced endurance performance after one week followed by a recovery to or above baseline in the period between one and six weeks. Given the reduced energy cost of the exercise despite the backpack, the extent of this adaptation cannot be determined from this study. To explain this improved exercise efficiency, we can speculate that humans are more efficient carrying weight in a modern backpack than under their skin as excess body fat. It is also possible that these untrained subjects became more comfortable with prolonged treadmill walking by their third test, and therefore improving their overall efficiency.
The results of physical performance testing are presented in Table 2. What is remarkable about these data is the lack of change in aerobic performance parameters across the 4-week adaptation period of the EKD. The endurance exercise test on the cycle ergometer was performed at 65% of VO2max, which translates in these highly trained athletes into a rate of energy expenditure of 960 kcal/hr. At this high level of energy expenditure, it is notable that the second test was performed at a mean respiratory quotient of 0.72, indicating that virtually all of the substrate for this high energy output was coming from fat. This is consistent with measures before and after exercise of muscle glycogen and blood glucose oxidation (data not shown), which revealed marked reductions in the use of these carbohydrate-derived substrates after adaptation to the EKD.
Examining the results of these two ketogenic diet performance studies together indicates that both groups experienced a lag in performance across the first week or two of carbohydrate restriction, after which both peak aerobic power and sub-maximal (60–70% of VO2max) endurance performance were fully restored. In both studies, one with untrained subjects and the other with highly trained athletes who maintained their training throughout the study, there was no loss of VO2max despite the virtual absence of dietary carbohydrate for 4–6 weeks. This whole-body measure of oxidative metabolism could not be maintained unless there was excellent preservation of the full complement of functional tissues including skeletal muscle (and mitochondrial) mass, circulating red cell mass, and cardiopulmonary functions.
The possibility raised by the first study of improved endurance time after keto-adaptation was not substantiated by the second study employing highly trained athletes without the complicating variable of major weight loss. It is thus likely that the increased endurance time in the Vermont study was due to improved efficiency (ie, less hobbling from a backpack than from an equal weight of internal body fat) and/or improved acclimation to the endurance test procedure. Such acclimation would not be expected in the second study, as the highly trained bicycle racers were well conditioned to the stationary ergometer at the start of the study. It is also worth noting that the bicycle racers remained weight stable (excepting the half kilogram of reduced muscle glycogen) across the 4 weeks of the EKD, which was equi-caloric with the baseline diet. Although 4 weeks is a relatively short period to assess small differences in energy efficiency between diets, this observation implies that there was no great reduction in the efficiency of energy metabolism after keto-adaptation.