Quote:
Originally Posted by Nancy LC
The thing is though, we don't even know if the shots actually work or not because they don't do double-blind clinical trials on them. Read this
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Yeah, I read the Atlantic article when it came out. As I'm sure you're aware, it's not quite as simple as "does the vaccine work, or doesn't it?" because the outcomes depend on who gets vaccinated. With something like a flu vaccine, where degree of immunity appears to depend on one's ability to muster an immune response to the shot, maybe there's little point to vaccinating the elderly and sick but a lot of point to vaccinating healthy young people. (I'm not suggesting that this is actually what we should do.)
The Japanese used to mass-vaccinate schoolchildren until about 20 years ago and there's some evidence that they were preventing ~40,000-50,000 excess deaths in the general population per year by doing so. If schoolchildren are efficient disease vectors, then an adequate herd immunity ought to protect vulnerable persons like the sick and elderly.
Anyway, I agree that it's a tough question to address. I got my H1N1 shot because I work in a high-density environment with a lot of young people, and I'm young enough myself that I'm on the border of the targeted groups.
As far as nutritional status and infection — medical research over the last few thousand years has followed this trajectory of
- How can we keep the sick from dying?
- How can we shorten the course of sickness?
- How can we prevent sickness in cases where we think we see a direct, obvious link between doing/not doing X and getting sick?
- How can we prevent sickness in cases where we're not so sure about the direct links?
When time and money are scarce, immediate concerns usually trump future concerns so the top of the list usually trumps the bottom. Sometimes answers from the top of the list trickle down to affect the other questions when we get lucky. And of course these days the whole track is affected by "How can someone profit from treating a sickness?" Not to mention that preventive nutrition in controlled studies and epidemiology are both really damned hard to do properly, as Gary Taubes has pointed out. Confounding factors, compliance issues, population composition issues...