Fri, Oct-05-18, 10:53
Plan: mostly milkfat
Stumbled across this today...
Diets differed only in
the composition of the fat and contained either 40% of energy
as MCT or LCT (soybean oil). The major differences between
diets in the resulting pattern of blood lipids were: 1) a reduction
in fasting serum total cholesterol concentrations with the
LCT, but not the MCT diet; and 2) a threefold increase in fasting
serum triglyceride concentrations with MCT, but not LCT,
diet. Moreover, 10% of the fasting triglyceride fatty acids were
medium chain and 40% were 16:O with the MCT diet. This
compared to 1 % and 20% for medium chain and 16:0, respectively,
with the LCT diet. In addition, there were increases in
16:1, 18:0, and 18:l in the triglycerides during MCT feeding.
The changes in fatty acids in triglycerides with MCT
feeding are consistent with the hypothesis that excess dietary
MCT cause a significant increase in the hepatic synthesis of
these fatty acids from MCFA through de novo synthesis and/or
chain elongation and desaturation.
Example of fat overfeeding (albeit soy oil, yum) lowering serum cholesterol. Interesting with the medium chain triglyceride increasing triglycerides/fat synthesis. Fasting triglycerides tripled, from around 100 to 300 mg/dl.
16:0 is palmitic acid, de novo synthesis of fatty acids in humans starts there, so it's a marker.
Fed to 150 percent of maintenance requirement, with 40 percent calories as either MCT or soybean oil. :blecch:
MCT oil is showing up cheap on grocery store shelves as "liquid coconut oil." Probably a place for therapeutic use, not sure what happens when you just add it willy nilly to the SAD.