I have been suffering from hot flashes and weight gain for the past NINE years. I have tried just about everything with limited success. One of my problems is that I start off taking my supplements and creams as prescribed but then start forgetting. I have a friend that is menopausal and has a bioidentical hormones pellet injected into her hip or butt about every 6 months and she says it makes all the difference in the world. As soon as I get the $ to do it I am going to try it. I figure that it will be cost effective considering how many supplements and diet aids I've tried. The link to the website that explains it if anyone is interested is www.sottopelletherapy.com/.