Remeber you should only be using Questran or Colestid IF you had your gallbladder out. As for Darvocet it DOES NOT bind bile it just makes you constipated like all pain relieveres can. So darvocet is like taking immodium just a lot more dangerous. All Questran and Colestid will do is help you turn back into a normal person. After having D long enough your body gets used to it and you will not lose weight. I take 1 g in the morning 1 g at night of Colestid. If it's too little you take it in the morning only if then still too much take it every other morning, if it's too little you call your doctor and he can adjust it to more. If some people see having D all the time as a good weight loss well it's not because having it all the time like that you aren't getting nutrients you need and you don't think as well. Also if you a lot and bad foods and you don't gain because of the D your body will get used to it sooner or later and you will begin to pack on the pounds. So don't depend on the D.