Got this warning from an online friend:
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If anyone has methylation cycle problems, like MTHFR, niacin can make it worse as it slows methylation. If that's the case you'll feel really bad, and energy will tank very rapidly.
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As always, keep monitoring body signals and listen to them. I have been tested for this gene, and it does not affect me. But it does affect DH.
And yet another reason to start slow, and build gradually.
I am having trouble sleeping, but I don't think it's the niacin: it's the US election results. If anything, niacin is helping me get back to sleep. Despite the 2 am waking (a symptom of cortisol problems) when I do wake up at my usual time, I feel rested, instead of that OMG-crashed feeling from not having good sleep at all.
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Originally Posted by GRB5111
Started the niacin protocol over the weekend and ordered a quantity of B-Complex that will arrive tomorrow. I'm embarking on another N=1 as well and learning as much as I can in the process.
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Thrilled to have company on this voyage! A close relative with stress problems is also starting the therapeutic level at this time, and reading the book.
Yes, the book occasionally startled me with the whole grains recc, but they wouldn't have known about Dr. Davis' work with grains. And there would have been no research about the MTFHR gene. They do repeat that not everyone gets results with niacin; and that just might be why.
One of the things the book repeats, that I just love, is, "X disease is not a drug-deficiency disease." It makes so much sense to give the body what it needs.
This was also the part that gave my relative pause: why do we need so much? How could we get this in an ancestral environment?
I think we didn't need it so much in the ancestral environment. I took up niacin largely because of
stress. As my GP put it, "literal killer stress." Modern life, and modern mayhem, and poor diet for decades: that's going to add up and affect the brain; which the book does discuss.