My doctor recently Rx me to begin both Glucophage and a restrictive LC diet. I have been shedding almost 1lb/day. I have Insuline Resistant PCOS and Hypothyroidism. The diet and Rx combo are something that their office suggests to all PCOS patients and they have a great success rate with both weight loss and pregnancy achievement. The LC diet is similar to Atkins Induction and maintenance is similar to SBD. Right now I can only eat meat, fats, oils, nuts, heavy cream, and non-starchy veggies. They advise one cheat meal per week. Also, I have zero side effects from the RX because of the LC diet (the only time I feel sick is when I cheat). I don't remember what my dose is but I take three large XR pills with dinner.