Thu, Sep-10-15, 14:24
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Senior Member
Posts: 15,075
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Plan: mostly milkfat
Stats: 190/152.4/154
BF:
Progress: 104%
Location: Ontario
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Quote:
Can we explain the differences?
The 2012 study fed the control group a diet low in sugar, including fish oil and antioxidants. Some scientists have suggested that because the control group had a moderate diet anyway, they may have also been slightly calorie restricted. Overall health in both groups was good, and even the control group lived longer on average than expected.
The 2014 team was less fussy with the control group's diet, giving them more sugar and a higher calorie intake. Some people argue they only found more encouraging results because the control group was eating more of a 'Western' diet and were less healthy in comparison.
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I think this is key. But the monkeys will have been fed the same diet--one group the Western diet ad-lib, the other the same high-sugar diet, but restricted.
I wonder if the strains of mice that respond positively to calorie restriction aren't the ones most prone to develop elements of the metabolic syndrome, diabetes, etc.? Making calorie restriction effective if you had planned on eating a diabetes-inducing diet, and if you were prone to developing insulin resistance etc. |