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I thought this was an interesting article: THE EFFECTS OF A 5MG DOSE OF DHEA

I've never been able to take a DHEA supplement. Mostly they come in 25-50mg doses. I end up with breast tenderness and weird menstruation. So far I'm tolerating the 5mg just fine. I've felt better than average too, and my ukelele playing has improved 25%! Perhaps they're connected. :lol:

Hmmm... this is interesting too:

http://blogs.webmd.com/womens-healt...-menopause.html

Quote:

Is over-the-counter DHEA safe?
Unlike in Europe, DHEA is available in the U.S. without a prescription. It is an active hormone, naturally produced by our adrenal glands. Our body will convert the DHEA to both estrogens (female hormones) and androgens (male hormones). I mention this as a breast cancer survivor once asked if she could take DHEA. I quoted a study by Genazzani (yes, the same scientist with the new study) published nine years ago in which postmenopausal women were given DHEA 25 mg pills for a year. Their blood levels of estradiol were 90 picograms. This is a level found in young, ovulating women.

Surprisingly, no undue stimulation of the lining of the uterus has been found in studies where menopausal women were given DHEA 25 mg or 50 mg. However, the women were followed for only 12 months. So we still do not know about long-term safety at such doses. If I had a patient using long-term DHEA I would want to be sure that their uterine lining was not being stimulated by newly created estrogen. This could be done with an ultrasound measurement of lining thickness.